Abstract

Overview

This study examines the long-term effects of exposure to extremely low frequency magnetic fields (ELF-MF) on blood coagulation variables in OF1 mice. It addresses a significant gap in research regarding haemostatic changes post ELF-MF exposure, emphasizing the potential connection to leukemia development.

Findings

• ELF-MF exposure was simulated at 50 Hz, 15 µT (rms) over a span of 14 weeks in a controlled setting with OF1 mice.
• Various blood coagulation tests were performed on the filial generation raised in the same ELF-MF conditions.
• Significant changes in coagulation variables were observed, particularly in female mice, including a noteworthy shortening of the Prothrombin Time (PT) and increases in the Activated Partial Thromboplastin Time (APTT) and Reptilase Time (RT).

Conclusion

The findings reveal that ELF-MF can potentially alter coagulation variables significantly, particularly in females, and suggest a correlation between ELF-MF exposure and increased hematological effects, potentially aiding in the understanding of leukemia mechanisms triggered by electromagnetic fields.