Genotoxic effects of intermediate frequency magnetic fields on blood leukocytes in vitro

Abstract

Overview

The investigation into the influence of electromagnetic fields, particularly at intermediate frequencies, has been limited despite their common presence in our environment due to various sources.

Methodology

This study focused on assessing the genotoxic effects specifically caused by intermediate frequency magnetic fields (IF-MF) on the DNA of canine and human blood samples in vitro. Blood was subjected to IF-MFs at frequencies of 123.90 kHz and 250.80 kHz with magnetic intensities marked at 630 A/m (0.79 mT) and 80 A/m (0.10 mT) over varied durations including 1-5 hours and extended periods of 20 and 24 hours. A unique divided Petri dish system was utilized to ensure varied induced currents at the same magnetic flux density.

Findings

• Exposure durations of 20 hours to IF-MF led to a statistically significant increase in DNA damage.
• Shorter exposure times did not reveal considerable DNA alterations.

Conclusion

The evidence underlines the potential risk intermediate frequency magnetic fields pose in causing significant genetic damage over prolonged exposures, reinforcing the necessity for careful consideration in their regulatory and exposure standards.