Call or Text: +1 727-610-1188

Free worldwide shipping on all orders over $100.00

Mobile phone specific radiation disturbs cytokinesis and causes cell death but not acute chromosomal damage in buccal cells: Results of a controlled human intervention study

This study, published in “Environmental Research”, titled, ” Mobile phone specific radiation disturbs cytokinesis and causes cell death but not acute chromosomal damage in buccal cells: Results of a controlled human intervention study”, conducted by Michael Kundi and colleagues, presents findings from the first controlled human intervention trial examining the acute cytotoxic and genotoxic effects of mobile phone-specific radiation. It’s crucial to dissect this study step by step to understand its significance, methodology, and what can be learned from it.

Importance of the Study

  1. First Controlled Human Intervention Trial: This is the inaugural study of its kind that rigorously investigates the impact of mobile phone radiation under controlled conditions, addressing a gap in previous research that often relied on questionnaire-based exposure assessments.
  2. Focus on Cytotoxic and Genotoxic Effects: The study zeroes in on whether mobile phone radiation causes chromosomal damage (genotoxicity) and cell death or disturbance (cytotoxicity) in buccal cells—cells from the inside of the cheek.

Key Findings

  1. No Chromosomal Damage Detected: The study did not find evidence of micronuclei formation, a marker of chromosomal damage, in buccal cells exposed to mobile phone radiation.
  2. Evidence of Cytotoxic Effects: There was a significant increase in binucleated cells and karyolitic cells in the exposed cheek cells. Binucleated cells are indicative of disturbed cell division, while karyolitic cells signal cell death.
  3. Potential Long-Term Health Effects: Although no acute chromosomal damage was found, the observed cytotoxic effects and cell cycle disturbances suggest that mobile phone radiation could potentially contribute to adverse long-term health effects.


  • Participants: 41 individuals were divided into two groups based on the level of specific absorption rate (SAR) exposure: low (0.1 W/kg) and high (1.6 W/kg).
  • Exposure: Participants were exposed to UMTS signal radiation on one side of the head for 2 hours on 5 consecutive days.
  • Analysis: Buccal cells were collected from both cheeks before and three weeks after exposure to assess for micronuclei and other nuclear anomalies.


This study’s controlled setup and methodology represent a significant improvement over previous research reliant on self-reported mobile phone use. By directly exposing participants to defined levels of radiation and observing the immediate and short-term effects on buccal cells, the research offers a clearer picture of the potential health impacts of mobile phone use.

Implications and Future Research

The findings indicate that while mobile phone-specific radiation may not cause acute chromosomal damage, it does have a clear impact on cell cycle processes and cell viability. These results are crucial for understanding the potential mechanisms through which mobile phone radiation might influence health over the long term, despite not causing immediate genetic damage.

Future research should aim to replicate these findings in larger cohorts, explore the mechanisms underlying the observed cytotoxic effects, and assess whether these cellular disturbances translate into increased health risks, particularly cancer, over prolonged periods of exposure.


The study specifically mentioned the use of a UMTS (Universal Mobile Telecommunications System) signal for the exposure. UMTS operates within the 3G mobile telecommunications networks and uses a set of frequencies that vary by country due to differing regulations. Common UMTS frequency bands include:

  • Band 1 (2100 MHz): The most widely used frequency for UMTS/3G networks. It is used in Europe, Asia, Africa, Oceania, Brazil, and India, among others.
  • Band 2 (1900 MHz): Used in North and South America.
  • Band 5 (850 MHz): Also used in North and South America, as well as in parts of Asia and Australia.
  • Band 8 (900 MHz): Used in Europe, Asia, Australia, and New Zealand.

These frequencies are not exclusive to UMTS; they are also utilized by other mobile telecommunications technologies, including GSM (2G) and LTE (4G) in some cases, depending on the band and the specific deployment strategies of mobile network operators.

Devices That Operate on UMTS Frequencies

  1. Mobile Phones and Smartphones: The most common devices that operate on UMTS frequencies, enabling voice calls, SMS, and data services.
  2. Tablets: Many tablets with cellular connectivity options support UMTS for data services.
  3. Mobile Broadband Modems and Routers: Devices such as USB dongles, MiFi devices, and portable hotspots that provide internet access over 3G networks.
  4. Wearable Devices: Some smartwatches and health monitoring devices with cellular capabilities can operate on UMTS networks for data and voice services.
  5. Vehicle Systems: Connected car systems that use UMTS for emergency services, navigation, and real-time traffic information.

In the real world, the transition from 2G and 3G networks to 4G LTE and 5G networks is ongoing. However, UMTS/3G remains relevant in many regions for voice and data services, particularly where newer network technologies are not yet fully deployed. Devices that support multiple frequencies and technologies (multi-band and multi-mode devices) can switch between different network types (e.g., from 3G to 4G or 5G) depending on availability and network conditions.

The study by Kundi et al. marks a significant step forward in our understanding of the biological impacts of mobile phone radiation. It shifts the focus from genetic damage to other cellular effects that might be equally relevant to understanding how mobile phone use could potentially contribute to health risks. The rigorous methodology and controlled exposure conditions set a new standard for future investigations in this field.

Free Worldwide shipping

On all orders above $100

Easy 30 days returns

30 days money back guarantee

Replacement Warranty

Best replacement warranty in the business

100% Secure Checkout

AMX / MasterCard / Visa