Abstract

Overview

Exposure to electromagnetic radiation fields from cell phones has been identified as a cause of thyroid dysfunction, leading to significant research in this area. Previous studies highlight the impact of nesfatin-1, a peptide, on thyroid functions, further promoting investigation into its role.

Objective

This study aimed to explore how nesfatin-1 influences thyroid function in rats subjected to electromagnetic radiation from cell phones.

Materials and Methods

• Study involved 30 adult male rats divided into three groups.
• Over a period of 30 days, various parameters like plasma nesfatin-1 levels, thyroid functionality, and thyroid tissue oxidative stress were assessed.
• Structural and apoptotic changes in the thyroid gland were studied through histological and immunohistochemical analysis.

Findings

Significant findings included:

• A marked decrease in plasma nesfatin-1 levels and diminished thyroid functionality.
• An increase in oxidative stress and apoptosis within the thyroid gland.
• A demonstrated correlation between decreased nesfatin-1 levels and elevated markers of thyroid dysfunction, oxidative stress, and apoptosis.

Conclusion

The study concludes that nesfatin-1 is significantly involved in the thyroid dysfunctions observed in rats exposed to mobile phone radiation, suggesting that electromagnetic radiation may interfere significantly with thyroid health.