Electromagnetic fields and oxidative stress: The link to the development of cancer, neurological diseases, and behavioral disorders

Authors: Lekovic �.

Year: 2025 Oct 21

Category: Epidemiology, Pathophysiology

Journal: Electromagn Biol Med

DOI: 10.1080/15368378.2025.2567872

URL: https://pubmed.ncbi.nlm.nih.gov/41117390/

Abstract

Overview

Recent epidemiological studies reveal a significant connection between electromagnetic field (EMF) exposure and increased incidences of malignant, cardiovascular, and neurodegenerative diseases. This paper aims to clarify possible mechanisms linking EMFs to physiological processes involved in disease development.

Background and Methods

  • Reviewed reports on oxidative stress, DNA damage, and disease risk from EMF exposure.
  • Developed the Electromagnetic Pathogenesis (EMP) model as a new conceptual framework.

Mechanisms

  • The EMP model suggests increased electron tunneling in the mitochondrial electron transport chain due to non-ionizing EMFs.
  • Induced electric fields amplify electron leakage during mitochondrial respiration, increasing free radical production.
  • Free radical formation links quantum tunneling, entropy, and Heisenberg’s principle, impacting aging and chronic disease.

Findings

  • Oxidative stress from EMFs disrupts cellular antioxidant defenses, especially through the release of iron and copper, generating harmful hydroxyl radicals near DNA.
  • Autoxidation of dopamine, when accelerated by metals, disrupts the dopamine system, implicating nervous system diseases and neuropsychiatric disorders like autism, addiction, and depression.
  • Fetal and embryonic brain tissues are highly susceptible; maternal oxidative stress can lead to malformations and neurodevelopmental disorders such as autism.
  • The human brain's social and reproductive networks are particularly vulnerable, linking EMF exposure to compromised social, reproductive behaviors, and reduced fertility rates.

Conclusion

  • Oxidative stress from EMF exposures is a primary mechanism leading to disease.
  • Reducing EMF exposure could decrease the incidence of diseases associated with oxidative stress, including cancer, cardiovascular, neurodevelopmental, and neurodegenerative diseases.
  • The EMP model underscores the link between long-term EMF exposure, oxidative stress, brain disorders, and behavioral changes, providing a basis for further research.
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