Abstract

Overview

This study examines the potential harmful effects of 1800 MHz electromagnetic radiation (EMR) on cell apoptosis when NIH/3T3 cells are exposed at a specific absorption rate (SAR) of 2 W/kg.

Findings

• Exposures were conducted intermittently across 12, 24, 36, and 48-hour durations.
• Methods used included Cell Counting Kit-8 and flow cytometry for assessing cell viability and apoptosis rates. Additionally, expressive analysis of the p53 protein and mitochondrial structure assessment was performed.
• Results indicated a significant decrease in cell viability and an increase in late-stage apoptosis, particularly after 48 hours of exposure.
• Substantial mitochondrial damage and changes in p53 protein expression were noted as significant factors in induced apoptosis.

Conclusion

This research provides strong evidence linking 1800 MHz EMR exposure to cellular apoptosis through mitochondrial damage and p53 protein expression upregulation, highlighting a potential health risk from electromagnetic fields of this frequency and duration.