Abstract

Overview

The World Health Organization (WHO) is compiling evidence regarding the impact of radiofrequency electromagnetic field (RF-EMF) exposure on health. This effort involves a series of systematic reviews conducted by experts to guide future exposure guidelines.

Objectives

• To systematically review how RF-EMF exposure affects male fertility and pregnancy outcomes based on observational human studies.
• This research adheres to WHO guideline development standards and the COSTER conduct guidelines.

Data Sources and Methodology

Data will be gathered from vast bibliographic databases including MEDLINE, Embase, and the EMF Portal, as well as grey literature and expert consultations. Eligibility criteria specific to infertility and adverse pregnancy outcomes will direct study inclusion.

Study Eligibility and Appraisal

Included studies will undergo rigorous screening and data extraction processes, utilizing the OHAT tool for bias assessment and the GRADE guidelines for evidence evaluation. Meta-analyses may be conducted if feasible to synthesize data and assess evidence certainty.

Conclusion

Publication of these review protocols aims to enhance transparency, reduce bias, and improve the overall review process by detailing methods and anticipated outcomes in advance.

Registration

The systematic reviews have been registered with Prospero (CRD42021265401 for SR3A and CRD42021266268 for SR3B).