Selenium supplementation ameliorates electromagnetic field-induced oxidative stress in HEK293 cells
Abstract
Overview
The increasing use of devices emitting 2.4 GHz electromagnetic radiation, particularly in communications and education, has prompted concerns about potential adverse health effects. This study explores the implications of these electromagnetic fields (EMF) on human embryonic kidney cells (HEK293), focusing on oxidative stress and cellular apoptosis.
Findings
- Experimental Setup: The research was structured into four groups: control, EMF exposure, and EMF exposure pre-treated with low and high doses of selenium (Se).
- Impact of EMF: Exposed groups showed increased lipid peroxidation and decreased activity of the antioxidants SOD and GSH-Px, accompanied by higher levels of apoptosis markers.
- Effect of Selenium: Selenium supplementation prior to EMF exposure mitigated oxidative stress by boosting antioxidant enzyme activities and reduced apoptosis by altering relevant proteins.
Conclusion
Selenium shows potential protective effects against cellular damage from 2.4 GHz EMF exposure, supporting its role as a powerful antioxidant. It prevents oxidative stress and inhibits cell apoptosis, highlighting its regulatory function in cellular defense mechanisms under EMF stress conditions.