Effects of RF-EMF Exposure from GSM Mobile Phones on Proliferation Rate of Human Adipose-derived Stem Cells: An In-vitro Study

Authors: Shahbazi-Gahrouei D, Hashemi-Beni B, Ahmadi Z

Year: 2016 Dec 1

Category: Biomedical Engineering

Journal: J Biomed Phys Eng

URL: https://www.ncbi.nlm.nih.gov/pubmed/28144594

Abstract

Overview

The increasing use of mobile phones raises significant concerns about the potential harmful effects of radiation emitted by these devices. This study aims to evaluate the impact of GSM 900 MHz phone radiation on the growth and proliferation of mesenchymal stem cells derived from adipose tissue.

Methodology

  • Frequency: 900 MHz
  • Intensity: 354.6 µW/cm², with pulse frequency at 217 Hz and 50% duty cycle.
  • Exposure Duration: 6 to 21 minutes daily over a period of 5 days.
  • Distance from Source: 20 cm
  • Assays: Cell growth and metabolism measured by MTT assay and cell viability by trypan blue test.

Findings

The study found statistically significant decreases in the proliferation rates of human ADSCs in all exposed groups compared to control, except in the 6 minutes/day exposure group, where no difference was noted.

Conclusion

Exposure to 900 MHz RF radiation from GSM mobile phones can reduce the viability and proliferation of human adipose-derived stem cells, depending on the duration of exposure. Recommendations are made for further investigation with varying frequencies, durations, and other cell types.

RF-EMF GSM human stem cells cell proliferation mobile phone radiation
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