Abstract

Overview

Various electronic devices, which we commonly use, radiate microwaves that can influence the functionality of biomolecules. Over an extended period, even ultralow field radiation has a significant impact on biomolecular structures. This study uses a coarse-grained model simulation to explore these effects.

Methodology

• A simple methodology for constructing the coarse-grained structure of proteins is adopted.
• The Langevin equation is solved under varying conditions to track structural changes in biomolecules.
• Each amino acid of a biomolecule is represented by beads, simulating the complexity of its chemical structure.

Findings

The model was applied to hen egg white lysozyme (HEWL), demonstrating its structural evolution under exposure to ultralow strength electromagnetic radiation. Notable findings include:

• Exposure of bioactive residues.
• Changes in the secondary structures confirmed by spectroscopic measurements.

Conclusion

The simulation reveals the adverse effects of ultralow field radiation on biomolecular structures, raising concerns about the safety of prolonged exposure to such fields. The generalized model offers potential for future studies on other biopolymers under similar conditions.