Biomolecular response to hour-long ultralow field microwave radiation: An effective coarse-grained model simulation

Authors: Anang Kumar Singh, P S Burada, Anushree Roy

Year: 2021

Category: Biophysics

Journal: Phys Rev E

DOI: 10.1103/PhysRevE.103.042416

URL: https://pubmed.ncbi.nlm.nih.gov/34005990/

Abstract

Overview

Various electronic devices radiate microwaves, which can disrupt the functionality of biomolecules in an ultralow field. Recognizing the importance of understanding these interactions, this study employs a simple methodology to explore the structural dynamics of biomolecules subjected to prolonged microwave exposure.

Methodology

  • Coarse-graining protein molecules into a simplified representation using beads.
  • Solving the Langevin equation under various working potentials to simulate microwave interaction.
  • Focusing on the protein, hen egg white lysozyme, to monitor its structural changes over a two-hour period.

Findings

The simulation provides insightful details on the extent of bioactive residues exposure and the state of secondary molecular structures under prolonged ultralow electromagnetic radiation. These structural insights are backed by spectroscopic measurements and provide a basis for understanding biological impacts.

Conclusion

The coarse-grained model outlined in this study highlights significant effects of prolonged ultralow radiation on biomolecular structure and functionality. It sets a foundation for further research into biopolymer dynamics under external perturbations, with potential implications for understanding biochemical responses to electromagnetic exposure, even at extremely low intensities, which may pose biological risks.

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