Abstract

Overview

The ongoing concerns about electromagnetic fields (EMF) and their impact on the nervous system foster important research, such as this study which explores how prolonged exposure to high-power microwaves affects male mice.

Findings

• Study involved forty-eight male Institute of Cancer Research mice exposed to L-band high-power microwaves at approximately 2.0 GHz across various power densities (0.5, 1.0, and 1.5 W/m2).
• Brain functions were assessed after different exposure times, examining brain morphology and alterations at the cellular level through specialized staining methods (HE and TUNEL).
• Analysis also included evaluation of cholinergic markers, oxidative stress markers, and c-fos expression to determine potential mechanisms of brain damage.
• Significant findings indicate that exposure to the highest power density (1.5 W/m2) results in extensive hippocampal and cortical damage, characterized by cell apoptosis, cholinergic dysfunction, and oxidative injuries.

Conclusion

Exposure to L-HPM is potentially detrimental to the nervous system, with effects intensifying with higher power densities and longer exposure durations. The results highlight a clear link between long-term EMF exposure at high intensities and significant neural disruption.