Abstract

Overview

The rapid increase in wireless phone use has raised concerns about potential health risks, specifically its association with adult glioma. This meta-analysis aims to evaluate the evidence regarding this connection.

Objective

To determine a possible association between wireless phone use and the risk of adult glioma.

Methods

• Search for eligible studies conducted via PubMed and Embase up until July 2017.
• Use of random- or fixed-effects model based on analysis heterogeneity.
• Evaluation of publication bias through Begg's funnel plot and Egger's regression asymmetry test.
• Conduction of subgroup analyses to assess the influence of various variables.

Results

The analysis included 10 studies focusing on the wireless phone use and glioma risk:

• Overall, ever use of wireless phones showed an odds ratio (OR) of 1.03 (95% CI=0.92-1.16) indicating high heterogeneity.
• No significant connection was noted in the temporal lobe tumor location subgroup.
• Significant risk increase found in long-term users (≥10 years) with an OR of 1.33 (95% CI =1.05-1.67).

Conclusion

While the general use of wireless phones was not markedly associated with increased adult glioma risk, the analysis indicated a heightened risk among long-term users, suggesting a potential health concern that requires more attention and further research.