Mobile-phone Radiation-induced Perturbation of Gene-expression Profiling, Redox Equilibrium & Sporadic- apoptosis Control in the Ovary of Drosophila melanogaster

Abstract

Overview

The exponential increase in the use of wireless devices has led to concerns about potential health effects. This study explores the impact of mobile phone radiation on the ovarian gene expression and cellular functions in Drosophila melanogaster.

Methods

• Subjects: Four-day-old adult female Drosophila melanogaster flies.
• Exposure: 30 min to mobile phone radiation, at a SAR of 0.15 W/kg and a SAE of 270 J/kg.
• Assays: ROS levels and apoptotic follicles were measured, alongside genome-wide microarrays analysis.

Findings

• Increased ROS levels by 1.6 times immediately post-exposure.
• Induction of sporadic apoptotic follicles, with a doubling in sub-population mass four hours post-irradiation.
• 168 genes displayed altered expression two hours after exposure related to metabolism, stress response, and apoptotic death.

Conclusion

Short-term exposure to mobile-phone radiation triggers significant oxidative stress and genetic reprogramming in Drosophila melanogaster’s ovaries. This suggests potential health risks associated with daily mobile phone usage, highlighting emergent cytopathic mechanisms and significant genetic alterations. It stresses the need for caution and further research into mobile radiation effects on human health.