Hippocampal alterations triggered by acute exposure of mice to GSM 1800 MHz mobile phone radiation

Abstract

Overview

The widespread use of wireless devices has sparked public concern over potential health effects, specifically regarding the radiofrequency electromagnetic radiation (RF-EMR) emitted. Recent research aims to decode RF-EMR's effect on cellular structures.

Methods

• Study involved C57BL/6 adult male mice, either exposed to GSM 1800 MHz mobile phone radiation or sham-exposed for control.
• Exposure lasted for 2 hours at an intensity range of 4.3-17.5 V/m.
• Analysis was conducted 6 hours post-exposure to evaluate changes in hippocampal lipidome and transcriptome.

Findings

Significant changes were observed in four fatty acids and in levels of SFA and MUFA, indicating a membrane remodeling in response to RF-EMR exposure. Additionally, expression of 178 genes was altered, impacting key biological processes including cell cycle, DNA replication and repair, and nervous system development.

Conclusion

Results suggest that acute exposure to mobile phone radiation might trigger hippocampal changes, contributing to observed protein alterations and potential memory deficits. This study offers crucial insight into the cellular impacts of RF-EMR.