Hippocampal Oxidative Stress Induced by Radiofrequency Electromagnetic Radiation and the Neuroprotective Effects of Aerobic Exercise in Rats: A Randomized Control Trial

Authors: Mina Rasouli Mojez, Abbas Ali Gaeini, Siroos Choobineh, Mohsen Sheykhlouvand

Year: 2021 Oct 25

Category: Neuroscience

Journal: J Phys Act Health

Institution: J Phys Act Health

DOI: 10.1123/jpah.2021-0213

URL: https://pubmed.ncbi.nlm.nih.gov/34697252/

Abstract

Overview

The study investigates the impact of moderate aerobic exercise on the antioxidant capacity in rat brains exposed to oxidative stress from radiofrequency electromagnetic radiation from cell phones over a 4-week period.

Methods

  • Assessment of biochemical markers such as malondialdehyde, catalase, glutathione peroxidase, and superoxide dismutase in male Wistar rats.
  • Experimental groups included rats subjected to moderate aerobic exercise, exposure to various radiofrequency waves, both exercise and exposure, and a control group using an inert device.

Findings

Significant increases in hippocampal cell death and malondialdehyde levels were observed in rats only exposed to radiation, while antioxidant enzyme activities were higher in groups involved in exercise, with or without radiation exposure.

Conclusion

Engagement in moderate aerobic exercise may mitigate the negative effects of radiofrequency electromagnetic exposure on hippocampal health by bolstering antioxidant defenses.

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