Nonparticipation selection bias in the MOBI-Kids Study
Abstract
Overview
The MOBI-Kids Study, conducted in 14 countries from 2010 to 2016, aimed to explore the potential effects of electromagnetic field exposure from mobile devices on brain tumor risks in the young population.
Background
- Focus on differences in mobile usage and personal characteristics between participants who completed the study and those who did not.
- Analysis of the impact of non-participation on study results.
Methods
Non-respondent questionnaires from 77 case and 498 control refusers across six countries were compared to responses from 683 interviewed cases and 1,501 control participants. Statistical methods included derivation of bias factors and the use of inverse probability weights in study analyses.
Results
- Regular mobile use was higher in younger participants who completed interviews compared to non-respondents.
- Small underestimation of cellular telephone odds ratios (ORs) observed due to selective non-participation, indicating potential selection bias.
Conclusion
A limitation by lower respondent numbers highlights a minor but notable underestimation in cellular telephone ORs which could be crucial when assessing exposure effects and risks associated with electromagnetic fields from mobile use.