Assessment of the effects of radiofrequency radiation on human colon epithelium cells

Abstract

Overview

The study investigates the impacts of radiofrequency radiation (RFR) on colon adenocarcinoma cells, focusing on apoptosis pathways.

Methods

• HT-29 colon cells exposed to 1800 MHz, 2100 MHz, and 2600 MHz RFR.
• Exposure durations: 3 hours continuous, 6 hours intermittent, and 6 hours continuous.
• Cell viability assessed by Trypan Blue exclusion; gene expression by qRT-PCR (CASP8, CASP9, CASP3, CASP12).

Findings

Significant findings include:

• Decreased viability of HT-29 cells at specific frequencies and exposure durations.
• Increase in caspase activity, indicating activation of apoptosis pathways.
• 2100 MHz showed more significant effects compared to 1800 MHz and 2600 MHz.

Conclusion

The study underlines the potential adverse effects of specific RFR frequencies and durations on human cells, calling for caution in their exposure. Different RFRs activate distinct cell death pathways through caspase signaling.