Immunotropic effects in cultured human blood mononuclear cells exposed to a 900 MHz pulse-modulated microwave field

Authors: Szymański Ł, Sobiczewska E, Cios A, Szymanski P, Ciepielak M, Stankiewicz W

Year: 2019 Dec 12

Category: Immunology, Radiobiology

Journal: J Radiat Res

DOI: 10.1093/jrr/rrz085

URL: https://www.ncbi.nlm.nih.gov/pubmed/31832654

Abstract

Study Overview

The study focuses on understanding the biological effects of electromagnetic fields (EMF), a notable environmental concern due to common devices emitting electromagnetic radiation like smartphones and Wi-Fi antennae. The interest is particularly centered around the impact on the human immune system.

Methodology & Experimentation

Researchers employed an innovative anechoic chamber for testing. Peripheral blood mononuclear cells (PBMC) sourced from healthy donors were exposed to a 900 MHz pulse-modulated radiofrequency radiation or left unexposed as a control. The exposure was duplicated with each session lasting 15 minutes. Parameters studied included T cell immunocompetence and the immunogenic activity of monocytes, using specific index measures and stimulatory agents.

Key Findings

  • Exposure led to increased immunogenic activity and T-cell responses initially which diminished after successive exposure.
  • Notable saturation of the interleukin-2 (IL-2) receptor was observed after two days of exposure, in contrast, the response to mitogen decreased following EMF stimulation.
  • PBMC showed resilience in handling stress induced by mitogens after being stimulated with 900 MHz radiation.

Conclusion

The study underscores that while electromagnetic radiation from common devices may alter immune system behavior temporally, PBMCs can adapt to EMS-induced stresses, with variations in reactiveness noted dependent on the nature and continuity of the exposure.

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