Effects of radiofrequency electromagnetic radiation emitted by mobile phones on rat parotid gland histology - an experimental study

Authors: Matei LI, Neag MA, Mocan LP, Sufle?el RT, Cu?a? A, Onofrei MM, Gherman LM, Armencea G, Mihu C, Ilea A, Mihu CM, Bordea IR, Inchingolo F, Dipalma G, Melincovici CS

Year: 2024 Oct

Category: Pathology, Experimental Research

Journal: Eur Rev Med Pharmacol Sci

DOI: 10.26355/eurrev_202410_36864

URL: https://www.europeanreview.org/article/36864

Abstract

Overview

With the rapid progression of telecommunication technology, mobile phones have become an integral part of modern life. Despite their ubiquity, the biological effects of their emitted radiofrequency electromagnetic radiation are not yet fully understood. This experimental study sought to investigate potential histopathological changes in the parotid gland and surrounding tissues following exposure to mobile phone radiation.

Materials and Methods

  • Thirty female Rattus Norvegicus rats divided into three groups:
    • Group 1: Exposed for 30 days
    • Group 2: Exposed for 60 days
    • Control group: Non-exposed
  • Exposure protocol: Two hours per day, phone call simulation, always directed towards the same side of the face.
  • Post-exposure assessments included inspection of orofacial structures and histological examination of parotid glands, overlying skin, oral mucosa, and cervical lymph nodes. Exfoliated squamous cells were stained to detect micronuclei.

Findings

  • Significant activation of fibroblasts observed in parotid gland septa in both exposed groups versus controls.
  • Cervical lymph node reactive changes, hyperkeratosis of oral epithelium, and activated fibroblasts in both dermis and oral mucosa lamina propria noted in both experimental groups.
  • Marked dermal and lamina propria fibrosis, especially prominent in the 60-day exposure group.
  • Increased vascular congestion and fibrosis detected in the parotid gland and other tissues after prolonged exposure (60 days) compared to both the 30-day group and controls.

Conclusion

These findings demonstrate that exposure to mobile phone radiation is associated with observable pathological changes in the parotid gland and adjacent tissues in rats. This research strengthens the connection between electromagnetic field exposure from mobile phones and potential tissue health risks.

electromagnetic fields mobile phones parotid gland rat study histopathology radiofrequency radiation tissue effects
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