Changes in dopamine, serotonin, their precursors and derivatives in prefrontal cortex of young male rats under chronic exposure to low-intensity Wi-Fi (in Russian)

Abstract

Overview

This study investigates the influence of chronic exposure to a low-intensity electromagnetic field emitted by a Wi-Fi device (2.45 GHz) on the content of biogenic amines, their precursors, and derivatives in the prefrontal cortex (PFC) of young male Wistar rats during early postnatal development.

Exposure Details

• Type: Wi-Fi device (2.45 GHz)
• Maximum power density: 5.83 μW/cm²
• Average power density: 0.46 ± 0.37 μW/cm²
• Exposure duration: 24 hours/day, 7 days a week

Findings

• Chronic EMF exposure led to notable changes in dopamine and serotonin levels, their precursors and metabolites within the PFC.
• These neurochemical alterations are linked with neurotransmitter disorders in the central nervous system.
• Such neurotransmitter disorders can result in behavioral disturbances, impaired social adaptation, and decreased cognitive abilities in rats.

Conclusion

The observed disturbances in the dopaminergic system of the prefrontal cortex at early postnatal stages underscore the necessity for rigorous hygienic assessment of long-term electromagnetic radiation exposure, especially concerning brain health. The findings highlight the potential danger of low-intensity EMF exposure and support the need for revising current permissible exposure limits, taking into account the brain’s neurotransmitter response to such fields. Further research is essential to fully elucidate the underlying neurotransmitter mechanisms mediating these neurobehavioral effects.