Myrtenal improves memory deficits in mice exposed to radiofrequency radiation during gestational & neonatal development via enhancing oxido-inflammatory, and neurotransmitter functions
Abstract
Overview
Exposure to Radiofrequency-electromagnetic radiation (RF-EMR) during sensitive developmental phases in mice has been linked to neuropsychological and neurobehavioral disorders like learning and memory impairments. This study investigates the effectiveness of Myrtenal (Myrt) in ameliorating these memory deficits.
Method
- Thirty-five male C57BL/6 mice were divided into five groups, with seven mice in each group.
- Groups were exposed to different treatments including vehicle control, RF-EMR (900 MHz) alone, RF-EMR with varying concentrations of Myrt, and RF-EMR with donepezil.
Findings
Myrt treatment significantly improved short-term memory in RF-EMR-exposed mice, enhancing endogenous antioxidant enzyme activity and proinflammatory cytokine levels, which protect the brain from oxidative-inflammatory stress. Additionally, Myrt helped maintain neurotransmitter homeostasis in the exposed mice.
Conclusion
The study confirms that RF-EMR exposure adversely affects short-term memory and modifies biochemical responses related to oxidative-inflammatory stress and neurotransmitters. It suggests that dietary intake of Myrt-enriched fruits might provide protective benefits to foeti and neonates exposed to RF-EMR.