CT2A Cell Viability Modulated by Electromagnetic Fields at Extremely Low Frequency under No Thermal Effects

Authors: García-Minguillán O, Prous R, Ramirez-Castillejo MDC, Maestú C

Year: 2019 Dec 24

Category: Molecular Science

Journal: International Journal of Molecular Sciences

Institution: Int J Mol Sci

DOI: 10.3390/ijms21010152

URL: https://www.mdpi.com/1422-0067/21/1/152

Abstract

Overview

The study focuses on the impact of electromagnetic fields (EMFs) at extremely low frequencies on CT2A cell lines. With ongoing debates about safety levels for EMF exposure, this research aims to shed light on cellular responses to EMF without thermal influence.

Findings

  • CT2A cells were subjected to various EMFs at different extremely low frequencies (ELFs) over both short (24 hours) and long (seven days) durations.
  • Initial exposure to a 30 μT EMF, similar to the Earth's, demonstrated frequency-dependent effects on cell viability after 24 hours.
  • Prolonged exposure (seven days) to 100 μT EMFs at varied ELFs notably decreased cell viability, specifically at 30 Hz frequency.
  • The study also investigated thermal effects by analyzing HSP90 expression and confirmed no thermal damage, suggesting other cellular mechanisms are at play.

Conclusion

The findings emphasize the significant impact of EMFs on cell viability without thermal damage, indicating a potential health risk that warrants further long-term investigation to evaluate safety standards.

electromagnetic fields cell viability low frequency thermal effects CT2A cells
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