Whole-body exposures to radiofrequency-electromagnetic energy can cause DNA damage in mouse spermatozoa via an oxidative mechanism
Abstract
Overview of Study
Artificially generated radiofrequency-electromagnetic energy (RF-EME), which is widespread due to mobile and Wi-Fi communications, has been studied for its potential biological impacts particularly in the male reproductive system.
Research Methodology
This research involved exposing unrestrained male mice to RF-EME at 905 MHz and 2.2 W/kg for 12 hours daily over one, three, or five weeks. Observations covered various aspects of the mice's testes and spermatological health.
Key Findings
- No gross changes or stress indications were observed in the testes in response to the RF-EME exposure.
- Mature epididymal spermatozoa showcased reduced vitality and motility after five weeks of exposure.
- Mitochondrial generation of reactive oxygen species in these spermatozoa increased post one week of exposure, alongside elevated DNA oxidation and fragmentation throughout the exposure course.
Conclusion
Despite the oxidative damage to DNA, RF-EME exposure did not hinder the sperm’s fertilization capability nor their support for early embryonic development. This study emphasizes the sensitivity of male germ cells as a metric for assessing the impacts of RF-EME, thereby hinting at potential health risks associated with prolonged RF-EME exposure.