Impact of exposure of diabetic rats to 900 MHz electromagnetic radiation emitted from mobile phone antenna on hepatic oxidative stress

Abstract

Overview

This study examines the impacts of continuous exposure to 900 MHz electromagnetic radiation (EMR), emitted from GSM mobile phone antennas, on diabetic rats over a span of 28 days. Such research is crucial given the increasing prevalence of mobile phones and the potential health risks their associated EMRs might pose.

Findings

• Experimental Setup: Type 2 diabetic male Sprague-Dawley rats (T2DM) were exposed to EMR for 24 hours each day. T2DM was induced via nicotinamide/streptozotocin. Rats were divided into four groups for comparison, including control groups with no EMR exposure.
• Biochemical Analysis: EMR exposure depicted mixed results—nonsignificant reduction in hyperglycemia and insulin levels, an increase in hepatic MDA and Nrf-2 levels, and enhanced activity of antioxidants such as SOD and catalase.
• Critical Outcomes: Significant decrease in phosphorylated Akt-2 may suggest potential negative implications like enhanced hepatic oxidative stress despite other biochemical increases.

Conclusion

The findings suggest potential biochemical alterations and stress markers in the liver due to long-term EMR exposure in diabetic conditions. Although some antioxidant activities were heightened, the decrease in pAkt-2 is concerning and could contribute to complications in diabetic patients. Further studies are needed to comprehensively understand these dynamics.