Magnetic Fields and Cancer: Epidemiology, Cellular Biology, and Theranostics

Authors: Massimo E Maffei

Year: 2022

Category: Epidemiology, Cellular Biology

Journal: International Journal of Molecular Sciences

Institution: International Journal of Molecular Sciences

DOI: 10.3390/ijms23031339

URL: https://www.mdpi.com/1422-0067/23/3/1339

Abstract

Abstract Overview

This comprehensive study explores the complex relationship between exposure to electromagnetic fields (MFs) and the development of certain cancers. By reviewing both human and animal cell studies, the paper delves deep into the potential hazards that such exposures represent, especially in residential and occupational environments.

Main Findings

  • Epidemiological evidence supports a positive association between exposure to extremely low frequency electromagnetic fields and certain types of cancer, notably leukemia, brain, and breast cancer.
  • The paper also reviews the cellular effects of MFs, emphasizing the production of reactive oxygen species (ROS) which may contribute to cancer development.
  • Applications of MFs in cancer diagnosis and treatment (theranostics), including the use of MRI and magnetic nanoparticles for drug delivery and selective cancer cell destruction, are also discussed.

Conclusions

The study highlights the dual role of MFs in cancer. While there is no definitive cause-effect proof, MFs are likely to enhance oxidative stress which could potentially stimulate oncogene expression, thereby increasing cancer risk.

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