Abstract

Overview

Mobile phones have been shown to have hazardous effects on the human renal system, reproduction and development, central nervous system, and immune function.

Objectives

This study aimed to investigate whether mobile phone prolonged radiofrequency (RF) radiation could affect healthy kidney cells in an in-vitro setting.

Materials and Methods

• Human kidney healthy cells in three groups were placed into three batches.
• The first and second groups (exposed groups) were exposed to a mobile phone simulator for 1 and 2 h/d, respectively.
• Irradiation was performed for 8 consecutive days.
• No radiation was applied to the third group (control group), which completed the assay cycle under identical conditions.
• Cells' survival was evaluated using MTT assay.
• Statistical significance was assessed using repeated measure ANOVA method (P < 0.05).

Findings

Radiation exposure from mobile phones simulator decreased kidney cell survival in exposed groups (up to 40%). ANOVA test revealed a significant decrease in cell survival in the exposed group compared to the control group (P = 0.014). No significant differences between the irradiated groups were found (P > 0.05).

Conclusion

Mobile phone exposure affects kidney cells' survival during an in vitro condition. Further in vivo studies on mammals are necessary to study the effects of mobile phone radiation on the kidney more comprehensively.