Abstract

Study of Chronic Chemical Intolerance

Overview

The Japanese chemical intolerance (JCI) study began in January 2012, focusing on a cohort of 7245 adults sourced from a population-based sample. The primary objective was to explore the persistent childhood constitutional and environmental factors influencing chronic chemical intolerance (CI).

Methods

• A six-year follow-up was completed with 4683 participants.
• Data were gathered via self-reported questionnaires covering medical history, childhood constitution, lifestyle, and housing environment.
• Assessment of differences between persons with enduring CI and controls without CI over the follow-up period.

Findings

Out of 2500 responses, the study identified strong correlations between chronic CI and conditions like motion sickness and allergic conjunctivitis during childhood. Notably, factors such as proximity to high-voltage power lines, certain domestic material use, and exposure to strong odors significantly increased CI risk. Conversely, some materials like carpets and plaster were linked with a decreased risk of CI.

Conclusion

This study suggests that certain childhood conditions might predispose individuals to develop chronic chemical intolerance later in life, possibly through inherent susceptibilities in the autonomic nervous system. The presence and influence of electromagnetic fields from high-voltage power lines represent potential environmental risks enhancing CI development.