The effect of 900-MHz radiofrequency electromagnetic fields during the adolescence on the histological structure of rat testis and its androgen and estrogen receptors localization

Authors: Gur FM, Keles AI, Erol HS, Guven C, Taskin E, Kaya H, Gur HE, Odaci E, Halici MB, Timurkaan S

Year: 01/2021

Category: Radiation Research

Journal: Int J Radiation Research

DOI: 10.18869/acadpub.ijrr.19.1.135

Abstract

Overview

Mobile phones emit radiofrequency-electromagnetic fields (RF-EMF). This study investigates the potential effects of cell phone-induced RF-EMF on the testicular tissue of adolescent rats.

Materials and Methods

  • Exposure: Test group subjected to 900 MHz RF-EMF; Control groups were not.
  • Test procedures: Histopathological and biochemical methods used on test tissues extracted from sacrificed rats.
  • Histological analysis: Tissues cut to 5 µm thickness and processed routinely.
  • Biochemical assays: Measurements of Malondialdehyde (MDA), glutathione (GSH), catalase (CAT), and superoxide dismutase (SOD).

Findings

  • Pathology: No histopathologic abnormalities observed across groups.
  • Receptor Localization: Similar androgen and estrogen receptor localization in all groups.
  • Oxidative Stress Indicators: Higher MDA and CAT, lower GSH in exposed group, no significant difference in SOD.

Conclusion

Exposure to 900 MHz RF-EMF induced oxidative stress in testicular tissues in adolescent rats, but the associated damage was too subtle to be detected by histopathological techniques used in this study, emphasizing the need for more sensitive detection methods.

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