A meta-analysis of the risk of salivary gland tumors associated with mobile phone use: the importance of correct exposure assessment

Authors: Vijayan K, Eslick GD

Year: 2022 Jul 11

Category: Epidemiology

Journal: Rev Environ Health

Institution: Rev Environ Health

DOI: 10.1515/reveh-2022-0055

URL: https://pubmed.ncbi.nlm.nih.gov/35822706/

Abstract

Overview

The study investigates the potential risk of developing salivary gland tumors from mobile phone usage and elucidates the necessity of precise exposure assessment.

Objectives

  • Examine the risk of salivary gland tumors related to mobile phone use.

Findings

The research integrated data across four databases, reviewing seven studies without restrictions on publication date or language. Using the Newcastle-Ottawa scale for quality assessment, it found:

  • No statistically significant association between mobile phone use and incidence of salivary gland tumors (OR=1.06, 95% CI=0.86-1.32).
  • Lack of evidence for publication bias.

Conclusion

Despite observing no substantial links between mobile phone usage and the development of salivary gland tumors, limitations inherent in the examined studies mandate cautious interpretation. These limitations underscore the importance of adequate exposure definitions to truly capture the carcinogenic potential of prolonged and heavy mobile phone use.

meta-analysis mobile phones salivary gland tumors epidemiology exposure assessment
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