A primary study on rat fetal development and brain-derived neurotrophic factor levels under the control of electromagnetic fields

Authors: DastAmooz S, Broujeni ST, Sarahian N

Year: 2023 Apr 19

Category: Neuroscience

Journal: J Public Health Afr

Institution: J Public Health Afr

DOI: 10.4081/jphia.2023.2347

URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395370/

Abstract

Overview

In prior studies, electromagnetic fields (EMF) have exhibited detrimental effects on the behavioral and biological aspects of humans and animals. Yet, impacts on bodily growth and brain-derived neurotrophic factor (BDNF) levels had not been thoroughly assessed before.

Objective

This study aimed to investigate the adverse effects of EMF exposure on spatial learning and motor functions in rats, while also exploring if physical activity could mitigate these harmful influences. A special focus was given to the anthropometric measurements and BDNF levels in the offspring of pregnant rats.

Methods

Twenty Albino-Wistar pregnant rats were evenly divided into EMF and control groups.
Post delivery, 12 male fetuses were randomly selected for ongoing assessment.
Measurements of body growth were taken at birth, 21 and 56 postnatal days using a digital caliper.
BDNF levels were determined using an ELISA kit, and bodyweight was monitored via a digital scale.

Findings

Analysis revealed significantly stunted body growth in the EMF-exposed group. BDNF levels were markedly reduced in this group compared to controls, indicating potential detrimental effects of EMF exposure on the neurological development of rat fetuses.

Conclusion

The findings underline significant concerns regarding the impact of EMF exposure on BDNF levels and developmental growth, suggesting potential long-term health risks in exposed populations.

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