Magnetocarcinogenesis: is there a mechanism for carcinogenic effects of weak magnetic fields?

Authors: Juutilainen J, Herrala M, Luukkonen J, Naarala J, Hore PJ

Year: May 23, 2018

Category: Epidemiology

Journal: Proceedings of the Royal Society B: Biological Sciences

URL: http://rspb.royalsocietypublishing.org/content/285/1879/20180590

Abstract

Abstract Summary of the Study

Overview

Extremely low-frequency (ELF) magnetic fields are classified as possibly carcinogenic to humans. This classification primarily arises from epidemiological studies indicating a potential association between childhood leukaemia and 50-60 Hz magnetic fields emitted from power lines.

Findings

  • The causal link between ELF magnetic fields and cancer remains unconfirmed, with animal and in vitro experiments providing limited support.
  • The study explores the radical pair mechanism (RPM), a phenomenon known for aiding magnetoreception in birds, which could ostensibly play a role in the carcinogenic effects of magnetic fields.
  • Cryptochromes, proposed as magnetosensitive molecules, might connect to biological processes relevant to cancer, positing a plausible link to childhood leukaemia.

Conclusion

The paper theorizes a biophysical mechanism, advocating further research into RPM and its involvement in carcinogenesis due to ELF magnetic fields. The strengths and weaknesses of existing evidence are also reviewed, with recommendations for future detailed studies.

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