Abstract

Overview

In recent decades, the use of pulsed electromagnetic fields (PEMF) in therapeutics has emerged prominently within the bioelectromagnetics field. Despite its potential, the scientific community lacks a unified biophysical mechanism to convincingly explain the interaction of low-level, non-thermal electromagnetic fields with biological systems.

Findings

• The study focuses on the radical pair mechanism (RPM) which posits that low-level external magnetic fields can influence chemical reactions between reactive oxygen species through specific interactions.
• This research utilized a computational approach with a generic PEMF test signal and RPM models of varying complexity to investigate the effects of electromagnetic fields on chemical outcomes.
• The orientation and amplitude of the PEMF signal, along with the waveform, significantly affect the chemical results, suggesting a method to manipulate chemical reactions in biological settings.

Conclusion

Experimental findings reinforce the importance of RPM in biological interactions, highlighting the potential of PEMFs to modulate radical pair reactions. These results advocate for further use of PEMF as a diagnostic tool to explore and optimize biological and chemical reactions manipulated by external magnetic fields.