Comparison of polymerization and structural behavior of microtubules in rat brain and sperm affected by the extremely low-frequency electromagnetic field

Abstract

Overview

This study investigates the effects of 50 Hz extremely low-frequency electromagnetic fields (ELEF) on microtubule polymerization and structural behavior in the brain and sperm of adult male rats.

Background

• Microtubule proteins, significant in memory and learning, are capable of generating electromagnetic fields.
• The influence of exogenous ELEF on microtubules is focused on, given their critical role in biological processes.

Results

• Treatment groups were assessed using plus-maze tests, and analysis of serum testosterone and corticosterone, alongside sperm evaluation.
• Despite no changes in hormone levels, anxiety behaviors, or sperm morphology, significant differences in sperm viability and motility were observed in ELEF-exposed subjects compared to controls.
• Increased microtubule polymerization and noticeable conformational changes in tubulin dimers were found in ELEF-exposed brain and sperm samples.

Conclusion

The research concludes that ELEF notably enhances microtubule polymerization and alters tubulin dimer structures, suggesting potential biomedical applications and indicating an important environmental effect.