Epigenetic dysregulation in various types of cells exposed to extremely low-frequency magnetic fields (Review)

Authors: Gianfranco Giorgi, Brunella Del Re

Year: 2021 Jul 21

Category: Cell Biology, Epigenetics

Journal: Cell Tissue Res

DOI: 10.1007/s00441-021-03489-6

URL: https://pubmed.ncbi.nlm.nih.gov/34287715/

Abstract

Overview

Epigenetic mechanisms are crucial for regulating gene expression without altering the DNA sequence itself, ensuring that gene expressions are appropriate in specific types of cells and at particular times. These mechanisms are vital for maintaining normal physiological conditions and preventing various diseases.

Findings

The study explores how extremely low-frequency magnetic fields (ELF-MFs), recognized as possible carcinogens, can influence epigenetic modifications across various cell types. It details observed epigenetic changes, such as DNA methylation, histone modification, and microRNA expression that correlate with ELF-MF exposure, potentially impacting disease risk and health.

Conclusion

Despite the limited research, evidence points to a significant association between ELF-MF exposure and epigenetic alterations. There is a strong impetus for further studies to clarify the underlying molecular mechanisms and assess the broader implications of these findings on human health.

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