The Importance of Subcellular Structures to the Modeling of Biological Cells in the Context of Computational Bioelectromagnetics Simulations

Authors: Jerbic K, Svejda JT, Sievert B, Rennings A, Fröhlich J, Erni D

Year: 2023

Category: Computational Bioelectromagnetics

Journal: Bioelectromagnetics

DOI: 10.1002/bem.22436

URL: https://onlinelibrary.wiley.com/doi/10.1002/bem.22436

Abstract

Overview

Numerical investigation highlights the complex interaction between electromagnetic fields and eukaryotic cells, emphasizing the need for specifically adapted computer models.

Methodology

  • Introduction of a method to determine current and volumetric loss densities in single cells and their compartments.
  • Usage of 3D models to simulate electromagnetic exposure of eukaryotic cells, examining various cell shapes and internal complexities.

Key Findings

The study investigates the spectral response of current and loss distribution within the cell compartments, considering material properties and geometric characteristics of these compartments.

Cells are modeled as anisotropic bodies with a distributed membrane system, akin to the endoplasmic reticulum, to better understand how electrical fields and currents distribute and where electromagnetic energy is absorbed.

Significant Impact

Results indicate that for frequencies utilized in 5G technology, the membranes contribute significantly to the absorption losses, leading to potential health risks related to electromagnetic exposure at these frequencies.

Conclusion

This research provides crucial insights into the microstructural impacts of electromagnetic fields on biological cells, contributing valuable data for assessing safety standards regarding 5G technologies.

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