Glioma incidence and survival variations by county-level socioeconomic measures

Authors: Cote DJ, Ostrom QT, Gittleman H, Duncan KR, CreveCoeur T, Kruchko C, Smith TR, Stampfer MJ, Barnholtz-Sloan J

Year: 2019 Jun 17

Category: Oncology

Journal: Cancer

Institution: Cancer Prevention and Research Institute of Texas

DOI: 10.1002/cncr.32328

URL: https://www.ncbi.nlm.nih.gov/pubmed/31206646

Abstract

Abstract Summary of Glioma Study

Overview

Recent studies have highlighted disparities in glioma incidence and survival rates associated with different socioeconomic statuses (SES), races/ethnicities, and urban versus rural locations.

Methods

  • Analysis of age-adjusted incidence rates of gliomas.
  • Calculation of hazard ratios for mortality, stratified by SES, race/ethnicity, and urban or rural status across various US regions.

Findings

Strong evidence shows the highest glioma rates in counties with elevated SES (rate ratio, 1.18; 95% CI, 1.15-1.22). This trend persists across different ethnicities, particularly among white non-Hispanic populations in urban settings. Notably, higher survival rates were observed in high SES counties after considering factors like age and surgical interventions.

Conclusion

The study concludes that both glioma incidence and survival rates are significantly linked with socioeconomic factors, particularly highlighted in urban counties and among certain racial groups. Such disparities suggest a potential effect of socioeconomic environment on health outcomes and necessitate further investigation into the underlying mechanisms.

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