Evaluation in humans of ELF-EMF exposure on chromogranin A, a marker of neuroendocrine tumors and stress

Authors: Touitou Y, Lambrozo J, Mauvieux B, Riedel M

Year: 2019 Nov 4

Category: Chronobiology

Journal: Chronobiol Int

DOI: 10.1080/07420528.2019.1683857

URL: https://www.ncbi.nlm.nih.gov/pubmed/31682468

Abstract

Overview

The study investigates the impact of chronic exposure to a 50-Hz magnetic field on Chromogranin A (CgA) levels in humans. CgA is significant as it is a marker found in neuroendocrine tumors and is linked to stress levels.

Methodology

  • Daily exposure was measured in 15 men (averaged age 38.0 ± 0.9 years), over periods ranging from 1 to 20 years.
  • Exposure measurements were taken using EMDEX II dosimeters, recording magnetic fields every 30 seconds for one week.
  • Blood samples were collected hourly from 20:00 h to 08:00 h to analyze CgA levels.

Findings

Exposed subjects’ CgA levels were compared with those of 15 unexposed men serving as controls. Despite the long-term exposure, there was no significant impairment in CgA levels; however, a trend towards lower levels was observed at exposure greater than 0.3 μT.

Conclusion

The research concludes that chronic exposure to ELF-EMF does not significantly affect CgA levels in the general adult male population though potential risks for more vulnerable populations, such as children and the elderly, should not be disregarded.

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