Hearing loss and vestibular schwannoma: new insights into Schwann cells implication

Abstract

Overview

Hearing loss (HL) is identified as the most common disorder of the sensory system affecting a significant portion of the global population. This condition is highly heterogeneous and involves various cell types within the cochlea of the acoustic nerve.

Findings

The study focuses on Schwann cells (SCs), which play a crucial role in axon insulation and myelin formation in peripheral nerves. SCs undergo transformations following injuries, exhibiting stem-like properties. The paper discusses the transformation of SCs, the development and progression of vestibular schwannoma (VS), and its implications for HL. Environmental factors, such as exposure to electromagnetic fields from everyday electronic devices, are also considered as potential contributors to HL and VS.

Conclusion

This review underscores the importance of linking molecular studies to clinical practices in otology to enhance diagnosis, predict outcomes, and guide therapeutic approaches. Additionally, the paper hints at broader environmental interactions influencing HL and VS, suggesting the necessity for future research in these areas.