Abstract

Abstract Summary

Overview

Cells and biological tissues when exposed to high-power THz radiation undergo various intracellular process changes. This study investigates the thermal effects by numerically modelling the scenario.

Findings

• Strong absorption of THz radiation by water molecules raises concerns about thermal impact.
• A finite-element model is used for estimating temperature changes using thermal conduction equations.
• Temperature changes depend on the frequency and fluence of THz radiation.
• Human dermal fibroblasts exposed to these conditions showed no significant difference in heat shock proteins expression compared to controls post 3-hour exposure.

Conclusion

The investigation underscores the crucial role of evaluating thermal effects in high-energy THz exposures. Despite no immediate statistically significant thermal effects noticed in proteins, the potential for subtle or long-term impacts should not be disregarded, emphasizing caution.